JENNIFER LYNN WILSON
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ˈsīən(t)əst  enjəˈnir

Using computational network techniques to discover engineering principles of
​multi-target, polypharmacology (MtPp) 
Scientific contributions: (images hyperlink to paper pdfs)
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Wilson, J.L., M. Wong, A. Chalke, N. Stepanov, D. Petkovic, R.B. Altman. “PathFXweb: a web application for identifying drug safety and efficacy phenotypes.” Bioinformatics. 2019 May 22. pii: btz419. doi: 10.1093/bioinformatics/btz419. [Epub ahead of print].
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Wilson, J.L. “A scientist engineer’s contribution to therapeutic discovery”. Experimental Biology and Medicine. 2018; 0: 1–8.
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Wilson JL, Altman RB. Biomarkers: Delivering on the expectation of molecularly driven, quantitative health. Exp Biol Med (Maywood). 2018 Feb;243(3):313–22.
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Sefcik LS, Wilson JL, Papin JA, Botchwey EA. Harnessing systems biology approaches to engineer functional microvascular networks. Tissue Eng Part B Rev. Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA; 2010 Jun;16(3):361–70.
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Wilson, J.L., R. Racz, T. Liu , O.Adeniyi, J. Sun, A. Ramamoorthy, M. Pacanowski, R.B. Altman. “PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development”. PLoS Comput Biol. 2018; 14(12): e1006614.
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Wilson JL, Dalin S, Gosline S, Hemann M, Fraenkel E, Lauffenburger DA. Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia. Integr Biol (Camb). 2016 Jul 11;8(7):761–74.
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Das, A., P. Merril, J.L. Wilson, B. Freshcorn, M. Paige, S. Capitosti, M. Brown, E. Botchwey. “Evaluating angiogenic potential of small molecules using genetic network approaches" Regenerative Engineering and Translational Medicine. 2018; 1-12.
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Adeniyi, O, Ramamoorthy A, Shuck R, Sun J, Wilson JL, Zineh I, Pacanowski M. An Overview of Genomic Biomarker Use in Cardiovascular Disease Clinical Trials. Clin Pharmacol Ther. 2019 Oct;106(4):841-846.
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Wilson JL, Kefaloyianni E, Stopfer L, Harrison C, Sabbisetti VS, Fraenkel E, et al. Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding. Mol Cancer Res. 2018 Jan;16(1):147–61.
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Wilson JL, Hemann MT, Fraenkel E, Lauffenburger DA. Integrated network analyses for functional genomic studies in cancer. Semin Cancer Biol. 2013 Aug;23(4):213–8.
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Gruenther, K., R. Bailey J. Wilson, C. Plucker, H. Hashmi (2009) “The Influence of Prior Industry Experience and Multidisciplinary Teamwork on Student Design Learning in a Capstone Design Course”, Design Studies
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(ORCID QR code)
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